Activating and Tranquilizing Effects of First-Time Treatment with Aripiprazole, Olanzapine, Quetiapine, and Risperidone in Youth
نویسندگان
چکیده
منابع مشابه
admittedpatientswere randomised to open-label treatmentwith aripiprazole, haloperidol, olanzapine, quetiapine, risperidone or ziprasidone for aminimum
Declaration of interest None. Second-generation antipsychotic drugs have been heralded as a significant advance in the treatment of patients with schizophrenia. However, except for clozapine, none has been conclusively shown to be superior in resolving the symptoms of schizophrenia. Head-to-head studies are lacking. There is little rational basis for selecting one over another other than a pati...
متن کاملSchizophrenia: risperidone and olanzapine increase time to discontinuation compared with quetiapine and ziprasidone.
Patients: 333 people aged between 16 and 65 years with schizophrenia (DSM-IV; mean age 40.8 years; 69% male) who discontinued treatment with the assigned atypical antipsychotic in the first phase of the study (for any reason). Exclusions: prior resistance to study drugs or treatment with clozapine for resistance; history of serious adverse reaction to study drugs; first episode schizophrenia; s...
متن کاملComparison of Capillary and Venous Drug Concentrations After Administration of a Single Dose of Risperidone, Paliperidone, Quetiapine, Olanzapine, or Aripiprazole
Risperidone, paliperidone, quetiapine, olanzapine, and aripiprazole are antipsychotic drugs approved for treating various psychiatric disorders, including schizophrenia. The objective of this randomized, parallel-group, open-label study was to compare finger-stick-based capillary with corresponding venous whole-blood and plasma concentrations for these drugs after administration of a single dos...
متن کاملComparison of Capillary and Venous Plasma Drug Concentrations After Repeated Administration of Risperidone, Paliperidone, Quetiapine, Olanzapine, or Aripiprazole
Quantification of blood levels of antipsychotic drugs may be useful for managing medication therapy. This open-label, parallel-group study was performed to compare finger-stick-based capillary with corresponding venous plasma concentrations for risperidone, paliperidone, quetiapine, olanzapine, and aripiprazole and their major metabolites after repeated dosing in patients with schizophrenia or ...
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ژورنال
عنوان ژورنال: Journal of Child and Adolescent Psychopharmacology
سال: 2016
ISSN: 1044-5463,1557-8992
DOI: 10.1089/cap.2015.0141